Researchers at Massachusetts General Hospital ( MGH ) have found the first evidence of a physical abnormality underlying CRPS. They reported four CRPS patients also diagnosed with the classical or hypermobility forms of Ehlers Danlos syndrome (EDS), inherited disorders of connective tissue. They hypothesized that "EDS might contribute to the development of CRPS.
They investigated whether or not headache and family history of headache were risk factors for CRPS. Their results suggested that headache and first-degree family history were risk factors but suggested further studies with larger numbers be carried out.
It seems that pilot studies are undertaken with promising results but little follow up is undertaken. It is my thought that there appears to be a hit or miss approach to research and not enough of which is publically funded. An axample of this is that UK research has found that taking 500mg of vitamin C after a colles wrist fracture can prevent development of complex regional pain syndrome. It seems to me that if the underlying thing addressed by this study was inflamation and inflamation is an issure in general with crps that a broader study could possibly find eg, that taking vitamin C post surgery could prevent the development of crps.