Monday, June 04, 2007

More research is needed to identify those more likely to develop crps/rsd and protocols should be in place for prevention of its development.

Not enough is known about predisposition to conditions such as complex regional pain syndrome. CRPS patients are left with chronic pain, vasodysregulation, and other symptoms. The predisposing factors are unknown. Genetic factors undoubtedly contribute, but have not yet been identified.

Researchers at Massachusetts General Hospital ( MGH ) have found the first evidence of a physical abnormality underlying CRPS. They reported four CRPS patients also diagnosed with the classical or hypermobility forms of Ehlers Danlos syndrome (EDS), inherited disorders of connective tissue. They hypothesized that "EDS might contribute to the development of CRPS.

The London Journal of Rheumatology September 2006, published an article about Japanese research "Headache may be a risk factor for complex regional pain syndrome".

They investigated whether or not headache and family history of headache were risk factors for CRPS. Their results suggested that headache and first-degree family history were risk factors but suggested further studies with larger numbers be carried out.

It seems that pilot studies are undertaken with promising results but little follow up is undertaken. It is my thought that there appears to be a hit or miss approach to research and not enough of which is publically funded. An axample of this is that UK research has found that taking 500mg of vitamin C after a colles wrist fracture can prevent development of complex regional pain syndrome. It seems to me that if the underlying thing addressed by this study was inflamation and inflamation is an issure in general with crps that a broader study could possibly find eg, that taking vitamin C post surgery could prevent the development of crps.

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