Saturday, August 15, 2009

New French study shows the effectiveness of vitamin c in prevenion of development of complex regional pain syndrome.

This is of particular interest to me as had this information been known at the time of my wrist fracture in 1998, this simple, inexpensive treatment could have prevented my nines years of pain.

Researchers at Centre Hospitalier, Rue Marcellin Berthelot, 02 000 Laon, France found that the incidence of reflex sympathetic dystrophy was five time times lower in a group give vitamin C orally for 45 days from the start of the fracture. They considered that this supported previous observations and lent credibility to the value of vitamin C administration as a prophylactic measure to prevent the occurrence of reflex sympathetic dystrophy in patients who undergo surgical treatment of a displaced fracture of the distal radius.

In July 2007 the Journal of Bone & Joint Surgery reported that Drs Zollinger, Tuinebreijer, Breederveld and Kreis, Department of Surgery, Red Cross Hospital, Beverwijk, The Netherlands had conducted a
randomized, controlled, multicenter dose-response study into whether vitamin C can prevent the development of Complex Regional Pain Syndrome in patients with wrist fractures.
The study concluded that Vitamin C reduces the prevalence of complex regional pain syndrome after wrist fractures. A daily dose of 500 mg for fifty days was recommended recommended.

"The study demonstrates the effectiveness of vitamin C in preventing CRPS I of the foot and ankle—a frequent complication in our control group (9.6%). The authors recommend preventive management by vitamin C."
I believe it is should be used routinely for prevention of CRPS post orthopedic surgery. Hopefully more research will be done to support the use of vitamin c to prevent development or complications of complex regional pain syndrome.

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