Saturday, January 22, 2011

New finding - a possible cure for chronic pain?

Diane Jacob highly regarded Canadian Physiotherapist posted on twitter  about this finding that could lead to a possible cure for chronic pain.

The University of Toronto's neuroscientific researcher, Professor Min Zhuo, had the department's finding published in the journal Science. Professor Zhuo is chief editor of Molecular Pain (Molecular Pain considers manuscripts in pain research at the cellular, subcellular and molecular levels providing a forum for molecular pain scientists to communicate their research findings.) 

This study addresses the maintenance of plastic changes related to chronic pain. It is known that injury caused by peripheral inflammation, nerve ligation or amputation causes long-term enhancement of neuronal activity in the fore brain region called anterior cingulate cortex (ACC).

The Toronto research explores the role that a particular protein (kinase M zeta - PKMζ) plays in storing “memories” of pain and therefore enhancing the sensation of pain. Blocking the effect of this protein has the effect of  blocking behavioral sensitization and nerve injury related to chronic pain.

Understanding brain plasticity and the part it plays in pain has been used for a while now in creating effective brain retraining treatments such as mirror therapy for pain. Professor Zhuo's work is a new area of research utilizing this understanding of brain plasticity that has potential for effective new treatments.

1 comment:

pain management emr said...

Great post! I wish this new findings can really help to cure the chronic pain of the patients. Thanks for sharing.

-mel-

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