Saturday, April 16, 2011

Pain and the immune system - a really interesting article.

Dr Nancy Sajben writes about the activation of glia and the immune system in her article "Pain and the immune system" This article fits neatly with my post about a promising new treatment for CRPS/RSD.

Dr Sajben says that the study of glia is early days but shows promise for development of drugs that can "distinguish activated glia for targeted treatment, new methods of visualizing glia, nefunds for research in thew sites for possible medicines and nanotechnology to deliver medication directly to the inflammation."

She also mentions the very real need for research in the area of pain in the USA. We have a similar problem here with reports recently of cuts to science.


Richmond Stace said...

The immune system is a key player in pain and maintenance, with a now significant amount of research pointing towards the interaction with the nervous and endocrine systems. Applying this knowledge in a pharamcological sense and also in prescribing exercise and other physical treatments. For example, we know that catastrophising has an effect upon inflammation, i.e. immune activity. Therefore, creating the right 'safe' context for exercise and probably timing should be a standard consideration. Stress and the immune system activity is a well understood and again provides an opportunity to intervene in an effective way to decrease the 'threat' value and work to desensitise excited body systems. There's much potential and it is very exciting and increasingly optimistic.

Usiku (oo-SEE-koo) said...

As science returns to the foundations of the interconnected workings of our cells, we should all prosper - not just from a healing of bodily dysfunctions but also from a maximizing cell performance. It'll be good to see greater specifics that can help map out what natural methods can reduce or repair breakdowns in our biochemical processes for certain dis-eases and restore balance and a better life.

jeisea said...

Thankyou Richmond and Usiku for your comments.

I agree with you Richmond that there is "potential and it is very exciting and increasingly optimistic". Your point about decreasing "the 'threat' value and workworking to desensitise excited body systems" is very important.

Well said Usiku. The time has also come to stop being precious about specifics confined to one area and to have regard for the whole of what is known. Man is not just a sum of its parts. The interconnectedness, the synergism and overlaying of what we know may lead us forward.

Barbara K. said...

This is such a useful set of information and comments. thanks

I admire your persistence in exploring new ways of approaching CRPS. I have passed your blog info along to many people

jeisea said...

Thanks Barbara. I appreciate both your comment and your help. I say again I am not qualified in this area. My search for information was driven mostly by desperation after I was told by my specialist, "there is nothing we can do to help" with the suggestion I use the internet. Along the way many have commented, offered links, suggested ways forward. Many involved in research have shared their information and patiently explained things. Many who work in the area of pain management, physical therapy, neuroscience etc have also helped. To all I am very grateful. For me, the search has paid off as I'm still in remission (for the second time). I am also confident of having the knowledge and resources to help myself if CRPS does recur.

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